upper gi - overview

Signet-ring cell carcinoma

Ralf Kiesslich, Prof. Dr.: Nov 24, 2009

42 year old female patient reported about indigestion and loss of appetite, especially for meat.
Former endoscopy revealed gastric cancer in a single random biopsy. Subsequent examinations including CT scan and endosonography as well as repeated gastroscopy with multiple biopsies could not confirm the presence of cancer.
Genetic testing prooved that the biopsy with the malgignant content was from the patient.
Endomicroscopy was performed to identify malignant changes of the mucosa.

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Barrett Esophagus

Ralf Kiesslich, Prof. Dr.: Jul 24, 2009

56 year old male patient with long standing reflux symptoms with predominant heartburn.

Patient was treated with intermittent PPI therapy and was scheduled for upper endoscopy 12 months ago which revealed long segment Barrett’s esophagus.

Patient was currently re-scheduled for endomicroscopy evaluating the presence of Barrett’s epithelium and associated dysplasia.

Endomicroscopy was performed with fluorescein intravenously (5ml; 10%) as contrast agent.

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Barrett's associated cancer

Ralf Kiesslich, Prof. Dr.: Aug 05, 2009

61 year old male patient with increased dysphagia was presented for endoscopic evaluation. The Patient suffered from reflux since decades and weight loss occurred during the last six months.

Thoracic and epigastric pain was treated with analgesic (OTC). Upper Endomicroscopy was performed with fluorescein intravenously (5ml; 10%) as contrast agent.

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